Release date: 2008-01-08
Hong Kong Report: Surgical Margins Pose a Threat to Survival in Nasopharyngeal Carcinoma Patients
According to a study conducted by the Prince of Wales Hospital at the Chinese University of Hong Kong, the presence of residual cancer cells at the surgical margins following surgery for locally recurrent or persistent nasopharyngeal carcinoma significantly affects patient survival. The term "surgical margin" refers to the distance between the edge of the removed tumor and the nearest cancerous tissue. In this study, researchers analyzed data from 79 patients with nasopharyngeal carcinoma who had experienced local recurrence or persistence after radiotherapy, spanning from November 1987 to November 2003 (61 males and 18 females, with an average age of 48 years). These patients were categorized into three groups based on their surgical margin status: negative, critical, and positive. The results showed that the 5-year survival rates were 77% for the negative margin group, 46% for the critical margin group, and just 23% for the positive margin group. This clearly highlights the significant impact that surgical margin status has on long-term survival outcomes for patients with nasopharyngeal carcinoma. These findings emphasize the importance of achieving clear surgical margins during treatment to improve prognosis. ——Midi Medical Network
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