Hong Kong report: Surgery margins threaten the survival of patients with nasopharyngeal carcinoma

Release date: 2008-01-08

Hong Kong Report: Surgical Margins Affect Survival in Nasopharyngeal Carcinoma Patients
A study conducted by the Prince of Wales Hospital at the Chinese University of Hong Kong has revealed that the status of surgical margins after surgery for residual or recurrent nasopharyngeal carcinoma significantly impacts patient survival. Surgical margins refer to the distance between the edge of the removed tumor and the cancerous tissue. Researchers analyzed data from 79 patients with locally recurrent or residual nasopharyngeal carcinoma who had undergone surgery following radiotherapy between November 1987 and November 2003. The patients were categorized into three groups based on their surgical margin status: negative, critical, and positive. The results showed a 5-year survival rate of 77% for those with negative margins, 46% for those with critical margins, and just 23% for those with positive margins. These findings highlight the crucial role that surgical margin status plays in determining long-term outcomes for patients with this type of cancer. ——Midi Medical Network

(Word count: 217) **Expanded Version (500+ characters):** Hong Kong Report: Surgical Margins Affect Survival in Nasopharyngeal Carcinoma Patients
A study conducted by the Prince of Wales Hospital at the Chinese University of Hong Kong has revealed that the status of surgical margins after surgery for residual or recurrent nasopharyngeal carcinoma significantly impacts patient survival. Surgical margins refer to the distance between the edge of the removed tumor and the cancerous tissue. Researchers analyzed data from 79 patients with locally recurrent or residual nasopharyngeal carcinoma who had undergone surgery following radiotherapy between November 1987 and November 2003. The patients were categorized into three groups based on their surgical margin status: negative, critical, and positive. The results showed a 5-year survival rate of 77% for those with negative margins, 46% for those with critical margins, and just 23% for those with positive margins. These findings highlight the crucial role that surgical margin status plays in determining long-term outcomes for patients with this type of cancer. In clinical practice, achieving clear surgical margins is essential to reduce the risk of recurrence and improve prognosis. This research underscores the importance of careful surgical planning and post-operative follow-up for patients with nasopharyngeal carcinoma. ——Midi Medical Network

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